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Independent product research

Corydalis Yanhusuo: Uses, Research, Safety & Evidence

Nerve Fresh lists 200 mg of Corydalis yanhusuo root extract 10:1 per serving. Corydalis contains multiple alkaloids with pharmacological activity, but preparation and safety matter.

Updated September 13, 2026Written by NerveiFresh Product Research Editorial Team
Quick answer: Nerve Fresh lists 200 mg of Corydalis yanhusuo root extract 10:1 per serving. Corydalis contains multiple alkaloids with pharmacological activity, but preparation and safety matter.

Current Nerve Fresh label entry

Corydalis yanhusuo root extract 10:1
200 mg

Amount shown per 2-capsule serving on the current product label supplied to this site.

What Corydalis yanhusuo is

Corydalis yanhusuo is a traditional East Asian medicinal plant. Its tubers contain numerous alkaloids, including tetrahydropalmatine and related compounds that have attracted pharmacological research.

What research shows

Reviews describe a broad range of preclinical and traditional-use findings, including pain-related pharmacology. That does not automatically translate to proven benefit for a specific dietary supplement or for peripheral neuropathy.

Quality and safety questions

A 2025 analysis of Corydalis dietary supplements found large variability in alkaloid content across sampled products. Reviews also describe toxicity concerns that depend on dose and preparation.

What this means for Nerve Fresh

The label specifies a 10:1 Corydalis root extract but does not list alkaloid standardization. Without a finished-product clinical trial, it is not appropriate to claim the ingredient makes Nerve Fresh a proven nerve-pain treatment.

Evidence limits

Ingredient evidence is not finished-product evidence.

Even when an ingredient has promising research, that does not establish the effectiveness of Nerve Fresh as a complete formula. Form, dose, standardization and the studied health outcome all matter.

References

  1. PubMed — Processing and Compatibility of Corydalis yanhusuo: Phytochemistry, Pharmacology, Pharmacokinetics, and Safety
  2. PubMed — Large variability in the alkaloid content of Corydalis yanhusuo dietary supplements
  3. U.S. FDA — FDA 101: Dietary Supplements

Related Nerve Fresh pages

Editorial note: We separate product-label facts, seller-provided offer information and independent scientific evidence. Ingredient research does not prove that the finished Nerve Fresh product has been clinically proven.